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Mojtahedi, A., Thamake, S., Tworowska, I., Ranganathan, D

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During the first reaction, cystathionine β-synthase (CBS) condenses homocysteine (Hcy) produced by the methionine cycle and a serine molecule into cystathionine, while in the second step, cystathionine γ-lyase (CTH) hydrolyses cystathionine into α-ketobutyrate and Cys